● Recruiting

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Condition: Endometrial Cancer · Sponsor: Canadian Cancer Trials Group

PhasePhase 2

Planned participants393

Who can joinFemale, 18 Years to no upper limit

Healthy volunteersNo

About this study

This protocol tests de-escalated adjuvant treatment in patients with POLE-mutated or p53wt/NSMP (p53 wildtype/no specific molecular profile) early-stage endometrial cancer (EC). Patients may be enrolled in one of two sub-studies * EN10.A/RAINBO BLUE: POLE-mutated EC * EN10.B/TAPER: p53 wildtype / NSMP EC

This description comes directly from the study's public registry record.

Talk to the study team

Wendy Parulekar · 613-533-6430 · wparulekar@ctg.queensu.ca

Always discuss trial participation with your own doctor first.

Locations (114)

Alaska Womens Cancer Care	Anchorage, Alaska, United States	Recruiting
University of Arizona Cancer Center	Tucson, Arizona, United States	Recruiting
Cedars-Sinai Medical Center	Los Angeles, California, United States	Recruiting
Huntington Memorial Hospital	Pasadena, California, United States	Recruiting
Sutter Medical Center Sacramento	Sacramento, California, United States	Recruiting
UCHealth University of Colorado Hospital	Aurora, Colorado, United States	Recruiting
AdventHealth Porter	Denver, Colorado, United States	Recruiting
University of Florida	Gainesville, Florida, United States	Recruiting
University of Miami School of Medicine	Miami, Florida, United States	Recruiting
Sarasota Memorial Hospital - Venice	N. Venice, Florida, United States	Recruiting
Florida Cancer Specialists - Sarasota Downtown	Sarasota, Florida, United States	Recruiting
First Physicians Group-Sarasota	Sarasota, Florida, United States	Recruiting

+ 102 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05640999