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Study identifier: NCT05640843 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)

Condition: Monoclonal Gammopathy of Undetermined Significance · Smoldering Multiple Myeloma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhaseNA
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The researchers are doing this study to look at how butyrate levels change in participants' stool after they are on a- plant-based diet for at least 12 weeks. All participants will have monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM). We will compare how the plant-based diet, omega-3 fatty acid and curcumin supplements, and placebo (an inactive substance that looks like the study supplements) affect butyrate levels in participants' stool.

This description comes directly from the study's public registry record.

Talk to the study team

Urvi A Shah, MD, MS  ·  646-608-3713  ·  ShahNutrivention@mskcc.org

Alexander Lesokhin, MD  ·  646-608-3717

Always discuss trial participation with your own doctor first.

Locations (8)

Emory University (Data Collection Only)Atlanta, Georgia, United StatesRecruiting
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (All Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (All Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (All Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (All Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05640843