Condition: Chronic Coronary Syndrome · Sponsor: Tianjin Chest Hospital
In daily clinical routine, the evaluation of new-onset and stable chest pain (SCP) suggestive of chronic coronary syndrome (CCS) remains a challenge for physicians. Although coronary computed tomography angiography (CCTA) seems to be the first-line cardiac imaging testing (CIT) according to the recommendations from current guidelines, the optimal diagnostic strategy to identify low risk patients who may derive minimal benefit from further CIT is the cornerstone of clinical management for SCP. Recently, different diagnostic strategies were provided to effectively defer unnecessary CIT, but few studies have prospectively determined the actual effect of applying these strategies in clinical practice. Therefore, the OPERATE study was designed to compare the effectiveness and safety of two proposed diagnostic strategies in identification of low risk individual who may derive minimal benefit from CCTA among patients with SCP suggestive of CCS in a pragmatic randomized controlled trial (RCT).
This description comes directly from the study's public registry record.
Jia Zhou, MD · +8615522485560 · zhoujiawenzhang@126.com
Always discuss trial participation with your own doctor first.
| Beijing Chaoyang Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Hebei Petrochina Central Hospital | Lanfang, Hebei, China | Recruiting |
| Tianjin First Central Hospital | Tianjin, Tianjin Municipality, China | Recruiting |
| Tianjin Chest Hospital | Tianjin, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05640752