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Study identifier: NCT05638867 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI

Condition: Coronary Artery Disease · Percutaneous Coronary Intervention · Acute Coronary Syndrome  ·  Sponsor: China National Center for Cardiovascular Diseases

PhasePhase 4
Planned participants3944
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare short-term Triple Antithrombotic Therapy (DAPT + Rivaroxaban) followed by DAPT with standard DAPT in selected ACS patients with high ischemic risk. The main questions it aims to answer are: * Whether the intervention is effective in reducing ischemic events * Whether the intervention is safe from increasing bleeding events, especially severe or fatal ones Participants will be randomized to receive standard DAPT therapy for the entire study duration or low-dose rivaroxaban+DAPT for 3 months, followed by standard DAPT for the rest of the study duration. Patients enrolled should complete 5 follow-ups in the form of clinic visit or telephone call.

This description comes directly from the study's public registry record.

Talk to the study team

Jinqing Yuan, MD  ·  +86-10-68314466  ·  dr_jinqingyuan@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

Chinese Academy of Medical Sciences, Fuwai HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05638867