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Study identifier: NCT05638581 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

Condition: Wounds and Injuries · Shock, Hemorrhagic  ·  Sponsor: University of Alabama at Birmingham

PhasePhase 3
Planned participants1100
Who can joinAll sexes, 15 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume blood transfusions.

This description comes directly from the study's public registry record.

Talk to the study team

Shannon Stephens, EMTP, CCEMTP  ·  205-934-5890  ·  swstephens@uabmc.edu

Kiran Mansoor, MBBS  ·  713-500-9643  ·  Kiran.Mansoor@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (13)

University of Alabama at Birmingham, UAB HospitalBirmingham, Alabama, United StatesRecruiting
Los Angeles County + University of Southern California (LAC + USC) Medical CenterLos Angeles, California, United StatesNot Yet Recruiting
University Medical Center New Orleans LCMC HealthNew Orleans, Louisiana, United StatesNot Yet Recruiting
University of Maryland Medical CenterBaltimore, Maryland, United StatesNot Yet Recruiting
Washington University School of MedicineSt Louis, Missouri, United StatesNot Yet Recruiting
Atrium Health Wake Forest BaptistWinston-Salem, North Carolina, United StatesNot Yet Recruiting
University of Cincinnati Medical CenterCincinnati, Ohio, United StatesRecruiting
Oregon Health and Sciences University HospitalPortland, Oregon, United StatesNot Yet Recruiting
Penn Presbyterian Medical CenterPhiladelphia, Pennsylvania, United StatesNot Yet Recruiting
University of Texas Health Science Center HoustonHouston, Texas, United StatesNot Yet Recruiting
University of Texas Health San Antonio and University Health SystemSan Antonio, Texas, United StatesNot Yet Recruiting
Harborview Medical CenterSeattle, Washington, United StatesRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05638581