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Study identifier: NCT05636215 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A First-in-human Study of IBI354 in Subjects with Locally Advanced Unresectable or Metastatic Solid Tumors

Condition: Locally Advanced Unresectable or Metastatic Solid Tumors  ·  Sponsor: Innovent Biologics (Suzhou) Co. Ltd.

PhasePhase 1/Phase 2
Planned participants368
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2, open-label, multicenter study designed to evaluate the safety, tolerability, and DLTs to establish the maximum tolerated dose (MTD) or maximum administered dose (MAD), and the RP2D of sequential doses of IBI354 (study drug), and to explore and confirm the efficacy, safety and tolerability of IBI354 in subjects with locally advanced unresectable or metastatic solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

yuan lei  ·  8610-68585566  ·  yuan.lei@innoventbio.com

Always discuss trial participation with your own doctor first.

Locations (6)

Scientia Clinical Research LtdRandwick, New South Wales, AustraliaCompleted
Westmead HospitalSydney, New South Wales, AustraliaCompleted
Sunshine Coast University Private HospitalSunshine Coast, Queensland, AustraliaCompleted
Monash HealthClayton, Victoria, AustraliaCompleted
Peking University Cancer HospitalBeijing, Beijing Municipality, ChinaRecruiting
Affiliated Cancer Hospital of Chongqing UniversityChongqing, Chongqing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05636215