← Eichor
Study identifier: NCT05633654 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Condition: Triple Negative Breast Cancer  ·  Sponsor: Gilead Sciences

PhasePhase 3
Planned participants1514
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Gilead Clinical Study Information Center  ·  1-833-445-3230 (GILEAD-0)  ·  GileadClinicalTrials@gilead.com

Always discuss trial participation with your own doctor first.

Locations (356)

Alabama OncologyBirmingham, Alabama, United StatesRecruiting
Clearview Cancer InstituteHuntsville, Alabama, United StatesRecruiting
Palo Verde Hematology OncologyGlendale, Arizona, United StatesRecruiting
Mayo Clinic HospitalPhoenix, Arizona, United StatesWithdrawn
Arizona Oncology AssociatesPrescott Valley, Arizona, United StatesWithdrawn
Alta Bates Summit Medical CenterBerkeley, California, United StatesRecruiting
Community Cancer InstituteClovis, California, United StatesWithdrawn
PIH Health Whittier HospitalDowney, California, United StatesRecruiting
Compassionate Cancer Care Medical Group - IncFountain Valley, California, United StatesRecruiting
Los Angeles Cancer NetworkLos Angeles, California, United StatesRecruiting
USC Norris Comprehensive Cancer CenterLos Angeles, California, United StatesWithdrawn
Cedars-Sinai Cancer at Beverly HillsLos Angeles, California, United StatesRecruiting

+ 344 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05633654