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Study identifier: NCT05629871 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Biomarkers of Sleep-wake Cycle in Prodromal Alzheimer's Disease: Role in Cognitive Decline?

Condition: Neuropathology  ·  Sponsor: University Hospital, Montpellier

PhaseNA
Planned participants132
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

Alzheimer's disease (AD) is characterised by a progressive loss of memory and cognitive function. In the early stages of AD, there is a progressive accumulation of molecules: β-amyloid peptides (Aβ) in the brain. There is a link between the accumulation of Aβ peptides and the deterioration of sleep, but current knowledge does not confirmed this link. The objective of this study is to define whether there is a link between cognitive decline and sleep disorders. If a correlation is found, this could allow earlier treatment of sleep disorders in the longer term in order to slow the development of AD.

This description comes directly from the study's public registry record.

Talk to the study team

Claire Denis  ·  +33467333162  ·  claire-denis@chu-montpellier.fr

Yves Dauvilliers, MD  ·  +33467335219  ·  y-dauvilliers@chu-montpellier.fr

Always discuss trial participation with your own doctor first.

Locations (3)

University Hospital, MontpellierMontpellier, FranceRecruiting
University Hospital of PoitiersPoitiers, FranceNot Yet Recruiting
University Hospital of ToulouseToulouse, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05629871