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Study identifier: NCT05627375 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Best Antithrombotic Therapy in Patients With Acute Venous ThromboEmbolism While Taking Antiplatelets

Condition: Venous Thromboembolic Disease  ·  Sponsor: Centre Hospitalier Universitaire de Saint Etienne

PhasePhase 3
Planned participants1400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Venous thromboembolism (VTE) and atherosclerotic cardiovascular disease share common risk factors and frequently coexist in the same patients. Their management requires use of antithrombotic agents: anticoagulant therapy (AC) for secondary prevention of VTE recurrence, antiplatelet (AP) for secondary prevention of major adverse ischemic cardiovascular and cerebrovascular event (MACCE) in patients with atherosclerotic cardiovascular disease (coronary artery disease, atherosclerotic cerebrovascular disease, lower extremity peripheral arterial disease). Side effects of antithrombotic drugs are the 1st cause of emergency admission and hospitalization for an adverse drug reaction (mainly bleeding), and the combination of AC with AP strongly increases this risk.

This description comes directly from the study's public registry record.

Talk to the study team

Laurent BERTOLETTI, MD PhD  ·  (0)477829121  ·  laurent.bertoletti@chu-st-etienne.fr

Carine LABRUYERE  ·  (0)477120469  ·  carine.labruyere@chu-st-etienne.fr

Always discuss trial participation with your own doctor first.

Locations (28)

CHU AmiensAmiens, FranceRecruiting
CHU AngersAngers, FranceRecruiting
CHU Besançon - Hôpital Jean MinjozBesançon, FranceRecruiting
CHRU Brest - Hôpital la Cavale BlancheBrest, FranceRecruiting
Clinique du Parc - Castelnau-le -lezCastelnau-le-Lez, FranceRecruiting
CHU Clermont-Ferrand - Hôpital Gabriel MontpiedClermont-Ferrand, FranceRecruiting
CHU DijonDijon, FranceRecruiting
CH le Corbusier - FirminyFirminy, FranceRecruiting
CHU Grenoble - Hôpital la TroncheGrenoble, FranceRecruiting
CH Le Puy - Hôpital Emile RouxLe Puy-en-Velay, FranceRecruiting
CHU LimogesLimoges, FranceRecruiting
HCL - Hôpital Edouard HerriotLyon, FranceRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05627375