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Study identifier: NCT05620771 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk

Condition: Hepatocellular Carcinoma  ·  Sponsor: Northwestern University

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research is to compare progression free survival between two available systemic therapies - immunotherapy and tyrosine kinase inhibitors - after Therasphere® (yttrium-90) treatment in adult patients with advanced hepatocellular carcinoma. The immunotherapy consists of a standard-of-care treatment with Atezolizumab and Bevacizumab. Treatment with tyrosine kinase inhibitors consists of standard-of-care Lenvatinib or Cabozantinib.

This description comes directly from the study's public registry record.

Talk to the study team

Study Coordinator  ·  3126951301  ·  cancer@northwestern.edu

Always discuss trial participation with your own doctor first.

Locations (7)

Northwestern UniversityChicago, Illinois, United StatesRecruiting
Northwestern Medicine Kishwaukee HospitalDeKalb, Illinois, United StatesRecruiting
Northwestern Medicine Delnor HospitalGeneva, Illinois, United StatesRecruiting
Northwestern Medicine Grayslake Outpatient CenterGrayslake, Illinois, United StatesRecruiting
Northwestern Medicine Lake Forest HospitalLake Forest, Illinois, United StatesRecruiting
Northwestern Medicine Orland ParkOrland Park, Illinois, United StatesRecruiting
Northwestern Medicine WarrenvilleWarrenville, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05620771