Condition: Coronary Artery Disease · Sponsor: VA Office of Research and Development
Heart disease remains the leading cause of death in Veterans. Inflammation in the arteries of the heart may increase the risk of cardiac death. Patients with heart disease undergoing major surgery are at increased risk of complications after surgery, including heart attack, stroke, and death. The proposed research seeks to better understand the role of inflammation in the damage to the heart and blood vessels after major surgery. This research also seeks to identify the potential beneficial role of a safe medication, colchicine, which has direct effects on inflammatory cells and has been used in the treatment of inflammatory diseases for more than 2000 years, on reducing the rate of complications after surgery. With its quick onset of action and excellent safety profile, colchicine may have the potential to reduce risk of heart injury, stroke, or death after major surgery.
This description comes directly from the study's public registry record.
Jennifer Yudkevich · (718) 836-6600 · jennifer.yudkevich@va.gov
Taj Kaur · (212) 686-7500 · tajinder.kaur@va.gov
Always discuss trial participation with your own doctor first.
| Birmingham VA Medical Center, Birmingham, AL | Birmingham, Alabama, United States | Recruiting |
| VA Long Beach Healthcare System, Long Beach, CA | Long Beach, California, United States | Recruiting |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Gainesville, Florida, United States | Recruiting |
| VA Western New York Healthcare System, Buffalo, NY | Buffalo, New York, United States | Recruiting |
| VA NY Harbor Healthcare System, New York, NY | New York, New York, United States | Recruiting |
| Durham VA Medical Center, Durham, NC | Durham, North Carolina, United States | Recruiting |
| Louis Stokes VA Medical Center, Cleveland, OH | Cleveland, Ohio, United States | Recruiting |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Dallas, Texas, United States | Recruiting |
| Michael E. DeBakey VA Medical Center, Houston, TX | Houston, Texas, United States | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05618353