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Study identifier: NCT05617898 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Determining the Role of Social Reward Learning in Social Anhedonia

Condition: Psychosis  ·  Sponsor: University of Alabama at Birmingham

PhaseNA
Planned participants152
Who can joinAll sexes, 18 Years to 35 Years
Healthy volunteersNo

About this study

This is a clinical trial study that aims to evaluate the specificity of the relationship between reduced sensitivity to social reward and social anhedonia at both behavioral and neural levels. Individuals who recently experienced their first-episode psychosis will be recruited. Participants will be randomized 1:1 to motivational interviewing or a time- and format-matched control probe. At pre- and post-probe, participants will perform two social reward learning tasks in the scanner. With this design feature, we will examine the relationship between sensitivity to social reward and reduced subjective experience of social pleasure at both the behavioral and neural levels.

This description comes directly from the study's public registry record.

Talk to the study team

Junghee Lee, PhD  ·  205-934-8205  ·  jungheelee@uabmc.edu

Andrew Meddaugh, BA  ·  205-934-8203  ·  ajmeddaugh@uabmc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
University of California Los AngelesLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05617898