← Eichor
Study identifier: NCT05616130 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pathological Myeloid Activation After Sepsis and Trauma

Condition: Trauma Injury · Sepsis · Immunosuppression  ·  Sponsor: University of Florida

PhaseN/A
Planned participants255
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic stem cells of these patients? and Does the initial severe trauma injury create immunosuppression and increase risk of in-hospital sepsis? Participants in study will give blood samples and a waste sample of bone marrow at time of operative repair of traumatic orthopedic injuries, supply medical information and participate in surveys and assessments during recovery from their injury(ies). Researchers will compare severe trauma injury patients to elective hip repair patients to see if immunosuppression and specific development patterns occur in the trauma patient versus the otherwise healthy hip surgery patient.

This description comes directly from the study's public registry record.

Talk to the study team

Ruth Davis, BSN  ·  352-273-8759  ·  ruth.davis@surgery.ufl.edu

Jennifer Lanz, MSN  ·  352-273-5497  ·  jennifer.lanz@surgery.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UF Health at Shands HospitalGainesville, Florida, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05616130