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Study identifier: NCT05609877 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The NONA-LISA Trial

Condition: Respiratory Distress Syndrome in Premature Infant  ·  Sponsor: Rigshospitalet, Denmark

PhaseNA
Planned participants324
Who can joinAll sexes, 24 Weeks to 30 Weeks
Healthy volunteersNo

About this study

The NONA-LISA trial will be an investigator-initiated, multicentre, pragmatic, parallel-group, blinded RCT conducted at four university hospitals across Denmark. A total of 324 inborn premature infants will be included within 36 months at four neonatal intensive care units (NICUs) across Denmark (approximately 2 infants per month per unit). The aim is to compare LISA using a non-pharmacological approach alone with routine analgesic treatment combined with a non-pharmacological approach (according to local guidelines) regarding LISA failure defined as the need for positive pressure ventilation for 30 min or more (cumulated) within 24 hours after the procedure in infants born prior to 30 gestational weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Lise Aunsholt, MD, PhD  ·  +4561991137  ·  lise.aunsholt@regionh.dk

Niklas Breindahl, MD  ·  +4528566410  ·  niklas.breindahl@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (4)

Neonatalafsnittet, Børn- og Ungeafdelingen, Reberbansgade 15Aalborg, DenmarkWithdrawn
Department of Paediatrics (Intensive Care Neonatology) and Perinatal Research UnitAarhus, DenmarkRecruiting
Department of Neonatal and Pediatric Intensive Care, Blegdamsvej 9Copenhagen, DenmarkRecruiting
H.C. Andersen Børne- og Ungehospital, Kløvervænget 23C, Indgang 60Odense, DenmarkNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05609877