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Study identifier: NCT05606822 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract

Condition: Endoscopic Vacuum Therapy · Anastomotic Leak · Esophageal Perforation  ·  Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to learn about the best indications and techniques regarding endoscopic vacuum therapy (EVT) in patients with a transmural defect in the upper gastrointestinal (GI) tract (e.g. anastomotic leakage, Boerhaave syndrome, iatrogenic perforation, other). The main questions it aims to answer are: * What is the success rate of EVT for transmural defects in the upper GI tract? * What are the best indications for EVT in the upper GI tract? (e.g. etiology, patient characteristics, defect characteristics) * What are the best techniques for EVT in the upper GI tract? (e.g. EsoSponge, VACStent, vacuum pressure, intraluminal/intracavitary) Participants will be asked for informed consent to retrospectively and prospectively collect data on EVT.

This description comes directly from the study's public registry record.

Talk to the study team

Roos Pouw, MD, PhD  ·  +3120 4444444  ·  r.e.pouw@amsterdamumc.nl

Lisanne Pattynama, MD  ·  +3120 4444444  ·  l.m.pattynama@amsterdamumc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Amsterdam University Medical Centers, location VUmcAmsterdam, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05606822