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Study identifier: NCT05604534 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

Condition: Normal Physiology  ·  Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

Background: Magnetic resonance imaging (MRI), which uses strong magnets to get images of structures inside the body, is a valuable tool in modern medicine. But researchers are always looking for ways to improve this technology. To better understand how to use MRI to diagnose problems, researchers need to collect more data from scans of healthy people. Objective: To get MRI scans of healthy people to improve the measurements doctors can make from the images. Eligibility: People aged 18 years or older in good general health. Design: Participants will be screened. They will have a physical exam focused on their nervous system. They will complete questionnaires. Participants will have at least 1 MRI scan. The target of the scan may be the brain, liver, prostate, breast, or other body part. Before the scan, participants will remove any metallic objects. They will lie on a narrow table that moves into a long, narrow tube. They may have special pads placed around them to help them remain still. Participants will hear loud noises during the scan. They will get earplugs or earmuffs to wear to muffle the sound. They can communicate with the MRI technician and will have an emergency button to squeeze at any time if they want the scan to stop. The scan will take up to 2 hours. Some participants may be asked to perform tasks on a computer screen during the scan. Participants may return for up to 5 scans in 3 months. Some may have as many as 30 MRI visits per year. They may rema…

This description comes directly from the study's public registry record.

Talk to the study team

Whitney M Spencer  ·  (301) 402-6668  ·  whitney.spencer@nih.gov

Carlo M Pierpaoli, M.D.  ·  (301) 402-2289  ·  carlo@helix.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05604534