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Study identifier: NCT05603650 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

Condition: Oral Bacterial Infection · Oral Infection · Microbial Colonization  ·  Sponsor: University of California, Irvine

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwash, or water. The overall duration of the study will be approximately 180 days and will include approximately 5 visits and 15-30 minutes for each visit with a total of approximately 2.5 hours of your time. Additionally, fecal matter will also be collected in some subjects using a commercial collection kit.

This description comes directly from the study's public registry record.

Talk to the study team

Nicole Wakida, PhD  ·  949-824-4360  ·  nwakida@uci.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Beckman Laser Institute and Medical ClinicIrvine, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05603650