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Study identifier: NCT05602246 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS

Condition: Pelvic Organ Prolapse · Cystocele · Cystocele and Incomplete Uterovaginal Prolapse  ·  Sponsor: Charles University, Czech Republic

PhaseNA
Planned participants592
Who can joinFemale, 50 Years to no upper limit
Healthy volunteersNo

About this study

Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles. Clinically, these defects are often combined and/or may be bilateral. Hence, careful assessment and individualized planning of the surgical procedure is essential to optimize cystocele repair outcome. Several surgical techniques and approaches have been used for cystocele repair. After the ban on transvaginal meshes, the interest in native tissue repair has risen. Paravaginal defect repair is an effective surgery for paravaginal defect reconstruction. There is a current trend to utilize transvaginal surgery instead of more invasive transabdominal surgery. A novel method of transvaginal paravaginal defect repair - TOCR (transobturator cystocele repair) was suggested. The principle objective of the present trial is to compare its efficacy and safety to preexisting method of native tissue cystocele repair.

This description comes directly from the study's public registry record.

Talk to the study team

Vladimir Kalis, prof. MD PhD  ·  +420377105228  ·  kalisv@fnplzen.cz

Zdenek Rusavy, assoc. prof. MD PhD  ·  +420377105440  ·  rusavyz@fnplzen.cz

Always discuss trial participation with your own doctor first.

Locations (8)

Faculty of Medicine in Hradec Kralove, Charles UniversityHradec Králové, CzechiaNot Yet Recruiting
Medical Faculty, Ostrava UniversityOstrava-Poruba, CzechiaNot Yet Recruiting
Hospital Pardubice Region, Inc.Pardubice, CzechiaNot Yet Recruiting
Faculty of Medicine in Pilsen, Charles UniversityPilsen, CzechiaRecruiting
Hospital na Bulovce, 1st Medical Faculty, Charles UniversityPrague, CzechiaNot Yet Recruiting
Tomas Bata Regional Hospital in ZlinZlín, CzechiaNot Yet Recruiting
Košice Medical UniversityKošice, SlovakiaNot Yet Recruiting
Trenčianska univerzita Alexandra DubčekaTrenčín, SlovakiaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05602246