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Study identifier: NCT05600400 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Improving Sexual Quality of Life - Randomized Trial of Two vs Five MRI Guided SABR Treatments for Prostate Cancer

Condition: Prostate Cancer · Cancer of Prostate · Prostate Adenocarcinoma  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseNA
Planned participants144
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Prostate Stereotactic ablative body radiotherapy (SABR) is an established technique that delivers radiation in a non-invasive approach for men with prostate cancer. The treatment regimen is given in total of 5 fractions with one treatment per day at every other day or weekly sessions. Ultra-hypofractionated radiotherapy (UHRT) is an emerging monotherapy for localized prostate cancer however, several trials have observed demonstrating superior biochemical control of a two-fraction (HDR) over single-fraction approach. The study aims to compare an experimental shorter course of prostate ultra-hypofractionated radiotherapy (UHRT) that will deliver what is expected to be an equivalent amount of radiation as given in the standard 5 treatment regimen. UHRT is given in 2 treatments with one treatment a week for 2 consecutive weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Danny Vesprini, MD  ·  416-480-6100  ·  Danny.Vesprini@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05600400