Condition: Postoperative Delirium · Postoperative Stroke · Postoperative Cognitive Dysfunction · Sponsor: University Hospital, Basel, Switzerland
This international, multicentre prospective cohort study will assess whether perioperative duration and magnitude of mean arterial pressure (MAP) outside of an individual's cerebral autoregulation (CA) limits using near-infrared spectroscopy (NIRS) and transcranial Doppler (TCD) are associated with adverse neurological events. It is to investigate whether patients with a higher burden of cerebral haemodynamic insults have an increased incidence or poorer neurological outcomes. Associations between neurologic outcomes, neurobiomarkers and genetic tests will be explored.
This description comes directly from the study's public registry record.
Nuno V. Gomes, MD · +41 61 328 64 46 · nuno.gomes@usb.ch
Luzius A. Steiner, MD, PhD · + 41 61 328 64 74 · luzius.steiner@usb.ch
Always discuss trial participation with your own doctor first.
| Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel | Basel, Switzerland | Completed |
| Inselspital, Bern University Hospital | Bern, Switzerland | Recruiting |
| Cambridge University Hospitals and Brain Physics Lab | Cambridge, United Kingdom | Completed |
| Royal Papworth Hospital, Department of Anaesthesia and Intensive Care | Cambridge, United Kingdom | Completed |
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Source record: clinicaltrials.gov/study/NCT05595954