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Study identifier: NCT05595603 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage

Condition: Giant Cell Tumor of Bone  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhasePhase 2
Planned participants153
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to investigate whether zoledronic acid-loaded bone cement (4mg ZOL+ gentamicin PMMA ) as adjuvant method can decrease local recurrence in patients with giant cell bone tumor following intralesional curettage surgery. The hypothesis is that patients with local administration of zoledronic acid to the bone cement has lower relapse rate compared those with traditional bone cement(gentamicin PMMA ).

This description comes directly from the study's public registry record.

Talk to the study team

Meng Liu, MD  ·  13515711791  ·  liumeng80@163.com

Keyi Wang, MS  ·  17398046579  ·  wky82630965@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Affiliated Hospital of Zhejiang UniversityHangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05595603