Condition: Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8 · Sponsor: Jonsson Comprehensive Cancer Center
This phase II trial tests whether fisetin works to improve physical function in women who have received chemotherapy for stage I-III breast cancer treatment. Fisetin is a naturally occurring substance that is found in strawberries and other foods. Fisetin eliminates cells that have undergone a process called senescence. Senescence is when a cell ages and permanently stops dividing but does not die. Over time, large numbers of these cells build up in tissues throughout the body and can release harmful substances that causes inflammation and damages nearby healthy cells. Studies have shown that chemotherapy causes a build-up of these senescent cells. Giving fisetin may eliminate senescent cells and improve physical function in postmenopausal women who have received chemotherapy for breast cancer.
This description comes directly from the study's public registry record.
Mina S. Sedrak, MD · 310-825-3181 · msedrak@mednet.ucla.edu
Kelly Synold · 424-440-3877 · ksynold@mednet.ucla.edu
Always discuss trial participation with your own doctor first.
| UCLA Health Cancer Care in Alhambra | Alhambra, California, United States | Recruiting |
| UCLA Health Beverly Hills Primary & Specialty Care | Beverly Hills, California, United States | Recruiting |
| UCLA Health Burbank Primary & Specialty Care | Burbank, California, United States | Recruiting |
| City of Hope Comprehensive Cancer Center | Duarte, California, United States | Recruiting |
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | Recruiting |
| UCLA Health Primary Care in Marina del Rey | Marina del Rey, California, United States | Recruiting |
| UCLA Health Primary Care in Pasadena | Pasadena, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05595499