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Study identifier: NCT05595408 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma

Condition: Muscle Invasive Upper Tract Urothelial Carcinoma  ·  Sponsor: RenJi Hospital

PhaseN/A
Planned participants84
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

In our study, the ultra-deep sequencing of circulating tumor DNA (ctDNA) and urine tumor DNA (utDNA) were performed to assess whether ctDNA and utDNA can be used as predictive biomarkers for the detection of minimal residual disease (MRD) and early diagnosis of UTUC recurrence, and explored the role of ctDNA and utDNA detection of MRD in the prediction of adjuvant therapy efficacy and prognostic evaluation.

This description comes directly from the study's public registry record.

Talk to the study team

jiwei huang, M.D  ·  8613651682825  ·  huangjiwei@renji.com

Always discuss trial participation with your own doctor first.

Locations (1)

Renji HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05595408