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Study identifier: NCT05593055 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

Condition: Hypertension · Left Ventricular Hypertrophy  ·  Sponsor: Brigham and Women's Hospital

PhasePhase 4
Planned participants75
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The investigators' goal is to show that in hypertensive men and women with left ventricular hypertrophy (LVH) treatment with a mineralocorticoid receptor (MR) antagonist, versus a thiazide-like diuretic, will improve coronary microvascular function and cardiac efficiency, which will associate with improvements in LV structure and function. The investigators will achieve this through a randomized, controlled, basic experimental study involving humans (BESH).

This description comes directly from the study's public registry record.

Talk to the study team

Gail K Adler, MD, PhD  ·  781-223-2686  ·  gadler@bwh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05593055