← Eichor
Study identifier: NCT05590455 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis

Condition: Tuberculous Meningitis · HIV I Infection  ·  Sponsor: ANRS, Emerging Infectious Diseases

PhasePhase 2
Planned participants130
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Randomized phase II clinical trial which aims to assess the impact on 3-month mortality and safety of adding adalimumab to standard treatment (anti-tuberculosis drugs and corticosteroids) in HIV patients with tuberculosis meningitis in 3 countries (Brazil, Mozambique, and Zambia).

This description comes directly from the study's public registry record.

Talk to the study team

Vanessa MACHAULT, PhD  ·  +335 57 57 57 63  ·  vanessa.machault@u-bordeaux.fr

Olivier MARCY, MD PhD

Always discuss trial participation with your own doctor first.

Locations (3)

Laboratory of clinical research on STD/AIDS - IPEC/FIOCRUZRio de Janeiro, BrazilRecruiting
Instituto Nacional de SaudeMaputo, MozambiqueNot Yet Recruiting
Adult Infectious Diseases Centre, University Teaching HospitalLusaka, ZambiaNot Yet Recruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05590455