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Study identifier: NCT05587361 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Beta-Adrenergic Modulation of Drug Cue Reactivity

Condition: Tobacco Use Disorder · Nicotine Dependence · Cigarette Smoking  ·  Sponsor: University of Oklahoma

PhasePhase 4
Planned participants80
Who can joinAll sexes, 21 Years to 60 Years
Healthy volunteersYes

About this study

This study is designed to investigate the effects of a beta-adrenergic antagonist (Propranolol; 40 mg IR) and nicotine patch (14 mg) administered alone and in combination on neurobiological and behavioral responses to smoking cues in ongoing cigarette smokers. This is a basic experimental study in humans and participants will not take these medications for an extended period or make a cessation attempt as part of their involvement in this research project.

This description comes directly from the study's public registry record.

Talk to the study team

Jason A Oliver, PhD  ·  405-271-8001  ·  Jason-Oliver@ouhsc.edu

Isabel Brush, B.A.  ·  Isabel-Brush@ouhsc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Hardesty Center for Clinical Research and NeuroscienceTulsa, Oklahoma, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05587361