Condition: Surgical Site Infection · Sponsor: University of California, Irvine
The DECREASE SSI Trial (Decolonization to Reduce After-Surgery Events of Surgical Site Infection) is a two-arm multi-center individual placebo-controlled randomized (2,700 participants randomized 1:1) clinical trial to reduce post-discharge surgical site infection following open colon or small bowel surgery by comparing chlorhexidine bathing plus nasal mupirocin in the 30 days following discharge to soap without antiseptic properties (placebo) and placebo nasal ointment. This trial seeks to enhance the care of the 675,000 patients annually who undergo colon and small bowel surgery by finding simple and efficacious interventions to reduce SSI.
This description comes directly from the study's public registry record.
Susan Huang, MD, MPH · (949) 824-5073 · sshuang@hs.uci.edu
Raveena Singh, MA · (949) 824-9285 · ravsingh@hs.uci.edu
Always discuss trial participation with your own doctor first.
| Hoag Memorial Hospital Presbyterian | Newport Beach, California, United States | Recruiting |
| University of California, Irvine Medical Center | Orange, California, United States | Recruiting |
| University of California, Davis Medical Center | Sacramento, California, United States | Recruiting |
| University of California, San Francisco Medical Center | San Francisco, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05586776