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Study identifier: NCT05585411 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial

Condition: Bradyarrhythmia · Atrioventricular Block · Left Bundle Branch Area Pacing  ·  Sponsor: Yonsei University

PhaseNA
Planned participants450
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

PROTECT-SYNC study is a multicenter, randomized, controlled trial. A total of 7 medical centers across Republic of Korea will enroll 450 patients during 2 years of enrollment period, and followed for 2 years of follow-up period. The purpose of this study to compare the clinical outcomes of Left Bundle Branch Area Pacing (LBBAP) compared to Right Ventricular Pacing (RVP) in bradyarrhythmia patients who require high burden of ventricular pacing (\>40%).

This description comes directly from the study's public registry record.

Talk to the study team

TaeHoon Kim  ·  +82 02-2228-8467  ·  thkimcardio@yuhs.ac

Always discuss trial participation with your own doctor first.

Locations (8)

Bucheon Sejong HospitalBucheon-si, South KoreaRecruiting
GyeongSang National University Changwon HospitalChangwon, South KoreaRecruiting
Chungbuk National University HospitalChungju, South KoreaRecruiting
Asan Medical CenterSeoul, South KoreaRecruiting
Kyunghee University hospitalSeoul, South KoreaRecruiting
Seoul National University HospitalSeoul, South KoreaRecruiting
Seoul Saint Mary's HospitalSeoul, South KoreaRecruiting
Yonsei University Health System, Severance HospitalSeoul, South KoreaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05585411