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Study identifier: NCT05582993 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

Condition: Von Willebrand Disease (VWD)  ·  Sponsor: Takeda

PhasePhase 3
Planned participants24
Who can joinAll sexes, N/A to 17 Years
Healthy volunteersNo

About this study

The main aim of the study is to evaluate the effectiveness of prophylaxis with vonicog alfa (recombinant von Willebrand factor \[rVWF\]) in children. This study will enroll those participants who have been previously treated with VWF product or with a plasma-derived VWF (pdVWF) product. In this study, participants will be treated with vonicog alfa (rVWF) for 12 months. During the study, participants will visit the study clinic 5 times after treatment initiation.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (21)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Bleeding and Clotting Disorders InstitutePeoria, Illinois, United StatesRecruiting
Riley Hospital for Children Indiana University HealthIndianapolis, Indiana, United StatesRecruiting
University of Iowa Hospitals & Clinics PARENTIowa City, Iowa, United StatesRecruiting
Childrens Hospital of MichiganDetroit, Michigan, United StatesRecruiting
Michigan State University Center for Bleeding Disorders & Clotting DisordersEast Lansing, Michigan, United StatesRecruiting
Children's Health Care d/b/a Children's MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Cure 4 the KidsLas Vegas, Nevada, United StatesRecruiting
Rutgers - Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey, United StatesRecruiting
New York - Presbyterian/Weill Cornell Medical CenterNew York, New York, United StatesRecruiting
Medical University of South Carolina (MUSC)Charleston, South Carolina, United StatesRecruiting
Hemostase Clinique - Institut Cœur-Poumons (4eme étage aile est) Bureau 419Lille, FranceRecruiting

+ 9 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05582993