Condition: Opioid Use Disorder · Sponsor: Yale University
Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.
This description comes directly from the study's public registry record.
Frederick L Altice, MD · 203-623-2634 · frederick.altice@yale.edu
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| Yale University | New Haven, Connecticut, United States | Active Not Recruiting |
| Columbia University Global Health Research Center of Central Asia | Almaty, Kazakhstan | Recruiting |
| Den Sooluk Nuru | Bishkek, Kyrgyzstan | Recruiting |
| Institute for International Health and Education | Dushanbe, Tajikistan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05579470