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Study identifier: NCT05577819 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

Condition: Transthyretin Amyloidosis · Heart Failure · Heart Failure, Diastolic  ·  Sponsor: Massachusetts General Hospital

PhaseNA
Planned participants515
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Recent studies have shown that transthyretin amyloidosis (ATTR) can sometimes cause a type of heart failure where the pumping function of the heart is normal, also known as Heart Failure with Preserved Ejection Fraction (HFpEF) or diastolic heart failure. In this single center diagnostic study, we will evaluate for ATTR in patients with HFpEF in order to to determine how frequently this occurs and how we can predict which heart failure patients may have TTR amyloidosis. Our goal is to identify amyloidosis in heart failure patients earlier so that they can start treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Abbie Macher, BS  ·  617-643-6328  ·  ajmacher@mgh.harvard.edu

Laura Stockhausen, BS  ·  617-724-1339  ·  lstockhausen@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05577819