Condition: Tryptophan Metabolism Alterations · Celiac Disease · Sponsor: McMaster University
This is a prospective, randomized, double-blind, placebo-controlled exploratory trial to evaluate the effect of L-tryptophan supplementation on celiac-related symptoms in individuals who have biopsy-confirmed celiac disease (CeD) and symptoms non-responsive to a gluten-free diet (GFD). Fifty participants, aged 18 to 75 years, who self-report persistent CeD-related symptoms despite taking a GFD for more than 1 year and who score \> 40 on the Celiac Symptom Index (CSI) will be randomized to receive L-tryptophan or placebo for 3 weeks.
This description comes directly from the study's public registry record.
Gaston H Rueda, MD · 905 521-2100 · ruedag@mcmaster.ca
Utkarshini N Kirtikar, MSc · 905 521-2100 · kirtikau@mcmaster.ca
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| McMaster University | Hamilton, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05576038