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Study identifier: NCT05573126 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Condition: Hormone Receptor-positive Breast Cancer · Hormone Receptor Positive HER-2 Negative Breast Cancer · Metastatic Breast Cancer  ·  Sponsor: Ellipses Pharma

PhasePhase 1/Phase 2
Planned participants95
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to identify the optimal dose for EP0062 as monotherapy and in combination with standard-of-care therapies to assess its Safety, Tolerability, Pharmacokinetics, and Efficacy in Patients with Relapsed Locally Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Team  ·  +44 (0)20 3743 0992  ·  Enquiries@ellipses.life

Always discuss trial participation with your own doctor first.

Locations (14)

Yale School of MedicineNew Haven, Connecticut, United StatesCompleted
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Henry Ford HospitalDetroit, Michigan, United StatesRecruiting
Sarah Cannon Research InstituteNashville, Tennessee, United StatesRecruiting
Texas Oncology Baylor University Medical CenterDallas, Texas, United StatesRecruiting
Virginia Cancer SpecialistsFairfax, Virginia, United StatesRecruiting
Hospital 12 de OctubreUsera, Madrid, SpainRecruiting
Hospital Universitari Vall d'Hebron (VHIO)Barcelona, SpainRecruiting
Hospital Universitario Ramón y CajalMadrid, SpainRecruiting
NEXT Oncology Hospital QuironsaludMadrid, SpainRecruiting
Sarah Cannon Research Institute UKLondon, London, United KingdomRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05573126