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Study identifier: NCT05572229 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma

Condition: Multiple Myeloma  ·  Sponsor: University Hospital, Lille

PhasePhase 2
Planned participants74
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

The primary hypothesis of this study is that teclistamab SC in combination with daratumumab SC or lenalidomide will be safe and induce a high rate of VGPR or better in newly diagnosed multiple myeloma patients This is an open-label, multicenter, non-comparative, 2-cohort, 2-stage with interruption of enrollment for an efficacy and safety interim analysis, interventional Phase 2 study evaluating the efficacy and safety of a combination with Tec-Dara (Cohort A) or Tec-Len (Cohort B) in patients with newly diagnosed multiple myeloma who are not eligible for SCT.

This description comes directly from the study's public registry record.

Talk to the study team

Salomon MANIER, MD  ·  0320445962  ·  salomon.manier@chru-lille.fr

Always discuss trial participation with your own doctor first.

Locations (29)

Chu Amiens - Hopital SudAmiens, FranceRecruiting
Chru AngersAngers, FranceRecruiting
Ch D'AvignonAvignon, FranceActive Not Recruiting
Centre Hospitalier de La Cote BasqueBayonne, FranceRecruiting
Chu de BesanconBesançon, FranceRecruiting
Aphp Hopital AvicenneBobigny, FranceNot Yet Recruiting
Chu de CaenCaen, FranceRecruiting
Chu Dijon BourgogneDijon, FranceRecruiting
Ch de DunkerqueDunkirk, FranceActive Not Recruiting
Chu de GrenobleLa Tronche, FranceRecruiting
Centre Hospitalier de VersaillesLe Chesnay, FranceRecruiting
Chu de Lille, Hopital Claude HuriezLille, FranceRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05572229