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Study identifier: NCT05569772 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes

Condition: Glucose Intolerance After a Recent History of Gestational Diabetes  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhasePhase 3
Planned participants252
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Gestational diabetes (GDM) is an important contributor to the increasing prevalence of type 2 diabetes (T2DM). Women with glucose intolerance in early postpartum are a particularly high-risk group with about 50% who will develop T2DM within 5 years after the delivery. Moreover, women with a history of GDM progress more rapidly to T2DM compared to women with similarly elevated glucose levels. Early intervention after the index pregnancy is therefore crucial to prevent T2DM. With the SERENA project, the investigators aim to reduce the risk to develop T2DM with the long-acting GLP-1 agonist semaglutide in women with a recent history of GDM and glucose intolerance in early postpartum.

This description comes directly from the study's public registry record.

Talk to the study team

Katrien Benhalima, MD PhD  ·  16340614  ·  katrien.benhalima@uzleuven.be

Always discuss trial participation with your own doctor first.

Locations (13)

AZORGAalst, BelgiumRecruiting
UZAAntwerp, BelgiumRecruiting
ZASAntwerp, BelgiumRecruiting
AZ St Jan BruggeBruges, BelgiumRecruiting
ErasmeBrussels, BelgiumRecruiting
UZ BrusselBrussels, BelgiumRecruiting
Jan YpermanIeper, BelgiumRecruiting
AZ Groeninge KortrijkKortrijk, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumRecruiting
CHU de LiègeLiège, BelgiumRecruiting
Centre Hospitalier MouscronMouscron, BelgiumRecruiting
VitazSint-Niklaas, BelgiumRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05569772