← Eichor
Study identifier: NCT05568069 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Condition: Heart Failure  ·  Sponsor: University Hospital Southampton NHS Foundation Trust

PhaseNA
Planned participants2504
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

BRITISH is a UK multicentre trial of patients who have been diagnosed with heart failure due to Non-Ischemic Cardiomyopathy (NICM, or heart failure that is not caused by blocked heart arteries. Participants will be randomised into two groups. Half the participants will receive an Implantable Cardioverter-Defibrillator (ICD) and the other half will not. The aim of the study will be to compare all-cause mortality (death from any cause) between these two groups at 36 months, and longer-term to 10 years. The study has the potential to change international heart failure treatment guidelines and to improve how patients with this condition are managed.

This description comes directly from the study's public registry record.

Talk to the study team

Abigail Jones  ·  023 8120 5154  ·  a.b.p.jones@soton.ac.uk

Pedro Rodrigues  ·  023 8120 5154  ·  p.rodrigues@soton.ac.uk

Always discuss trial participation with your own doctor first.

Locations (47)

Wycombe HospitalHigh Wycombe, Buckinghamshire, United KingdomRecruiting
Derriford HospitalPlymouth, Devon, United KingdomRecruiting
Royal Bournemouth HospitalBournemouth, Dorset, United KingdomRecruiting
Durham & Darlington NHS Foundation TrustDarlington, Durham, United KingdomRecruiting
Royal Sussex County HospitalBrighton, East Sussex, United KingdomRecruiting
Essex Cardiothoracic CentreBasildon, Essex, United KingdomRecruiting
James Paget University Hospitals NHS FTGorleston-on-Sea, Great Yarmouth, United KingdomRecruiting
Portsmouth Hospitals University NHS TrustPortsmouth, Hampshire, United KingdomRecruiting
Southampton Clinical Trials UnitSouthampton, Hampshire, United KingdomNot Yet Recruiting
University Hospital Southampton NHS Foundation TrustSouthampton, Hampshire, United KingdomRecruiting
Kent & Canterbury HospitalCanterbury, Kent, United KingdomRecruiting
Maidstone Hospital, Maidstone & Tunbridge Wells NHS TrustMaidstone, Kent, United KingdomRecruiting

+ 35 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05568069