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Study identifier: NCT05555550 Synced from ClinicalTrials.gov · July 28, 2026
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Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

Condition: Glioma · Low-grade Glioma · Low Grade Glioma of Brain  ·  Sponsor: Children's Hospital of Philadelphia

PhaseEARLY_Phase 1
Planned participants30
Who can joinAll sexes, 1 Year to 21 Years
Healthy volunteersNo

About this study

The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 18F-Fluciclovine PET-MRI will be performed prior to initiation of therapy for LGG, and then 3 months, and 1 year after starting therapy. Changes in 18F-Fluciclovine uptake will be compared to changes in MRI measurements at 3 months and 1 year as compared to baseline.

This description comes directly from the study's public registry record.

Talk to the study team

Mariam Aboian, MD, PhD  ·  215-510-7661  ·  aboianm@chop.edu

Nazanin Maleki, MD  ·  malekin@chop.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Children s Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05555550