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Study identifier: NCT05552222 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Condition: Multiple Myeloma  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants1590
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare the efficacy of teclistamab in combination with daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexamethasone (DRd).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (270)

Banner MD Anderson Cancer CenterGilbert, Arizona, United StatesRecruiting
University of Arizona Cancer CenterTucson, Arizona, United StatesRecruiting
UCSF FresnoClovis, California, United StatesRecruiting
City of Hope DuarteDuarte, California, United StatesRecruiting
City of Hope Orange County Lennar Foundation Cancer CenterIrvine, California, United StatesRecruiting
Cancer and Blood Specialty ClinicLos Alamitos, California, United StatesRecruiting
Valkyrie Clinical TrialsLos Angeles, California, United StatesRecruiting
University of ConnecticutFarmington, Connecticut, United StatesRecruiting
Yale New Haven HospitalNew Haven, Connecticut, United StatesRecruiting
ChristianaCare Helen F Graham Cancer Center and Research InstituteNewark, Delaware, United StatesRecruiting
Memorial Healthcare SystemHollywood, Florida, United StatesRecruiting
AdventHealth Medical Group Blood & Marrow Transplant at OrlandoOrlando, Florida, United StatesRecruiting

+ 258 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05552222