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Study identifier: NCT05551793 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Regeneron AA Multicenter (Dupilumab)

Condition: Alopecia Areata  ·  Sponsor: Emma Guttman

PhasePhase 2
Planned participants76
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affecting more than 50% of the scalp) at the time of screening with a targeted 54 subjects completers through Week 48. AA subjects must have evidence of hair regrowth within the last 7 years of their last episode of hair loss; and have screening IgE ≥ 200 and/or have personal and/or familial history of atopy. Subjects will be randomized (2:1) to either receive weekly dupilumab or placebo for 48 weeks, with all subjects completing participation through Week 48 receiving an additional 48 weeks of dupilumab (through Week 96).

This description comes directly from the study's public registry record.

Talk to the study team

Giselle Singer  ·  212-241-3288  ·  giselle.singer@mssm.edu

Sharlene Martin  ·  212-241-3288  ·  sharlene.martin@mssm.edu

Always discuss trial participation with your own doctor first.

Locations (3)

University of California, IrvineIrvine, California, United StatesRecruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting
UR Dermatology at College TownRochester, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05551793