Condition: Hilar Cholangiocarcinoma · Sponsor: University of Leipzig
Bile duct cancer is often diagnosed after curative options are no longer available. Stent therapy is used to keep the ducts open and can be combined with photodynamic therapy (PDT) to extend life expectancy. PDT requires an injection of photosensitizer after which light of a particular wavelength is applied endoscopically to kill the cancer cells. Drawbacks include not only high costs and poor availability, but foremost that patients have to avoid direct sunlight for a period of weeks. Radio frequency ablation (RFA) together with stent implantation constitutes an alternative by which the cancer cells are killed through heat, also applied endoscopically. The RFA technology is more widely available and easier to deploy. However, it has not been studied extensively and no randomized trials exist comparing the two methods. This trial will compare survival in patients with a particular bile duct cancer depending on whether they receive PDT or RFA. Moreover, data will be collected on side-effects and quality of life.
This description comes directly from the study's public registry record.
Albrecht Hoffmeister, Prof.Dr.med. · +49-341-97-12240 · albrecht.hoffmeister@medizin.uni-leipzig.de
Marcus Hollenbach, Dr. med. · +49-341-97-12362 · marcus.hollenbach@medizin.uni-leipzig.de
Always discuss trial participation with your own doctor first.
| Uniklinik RWTH Aachen, Medizinische Klinik III | Aachen, Germany | Recruiting |
| Universitätsklinikum Augsburg; III. Med. Klinik | Augsburg, Germany | Recruiting |
| Vivantes Netzwerk für Gesundheit GmbH, Klinikum Friedrichshain, Innere Medizin/Gastroenterologie | Berlin, Germany | Not Yet Recruiting |
| Universitatsklinikum Bonn, Medizinische Klinik und Poliklinik I | Bonn, Germany | Recruiting |
| Universitätsklinikum Frankfurt, Medizinische Klinik 1 | Frankfurt, Germany | Not Yet Recruiting |
| Universitätsklinikum Freiburg, Medizinische Klinik II, Abteilung Gastroenterologie, Hepatologie, Endokrinologie & lnfektiologie | Freiburg im Breisgau, Germany | Recruiting |
| Universitätsmedizin Greifswald Klinik für Innere Medizin A | Greifswald, Germany | Recruiting |
| Site: Martin-Luther-Universitat Halle-Wittenberg, Universitätsklinik und Poliklinik für Innere Medizin I | Halle, Germany | Recruiting |
| Klinikum Hanau; Klinik für Gastroenterologie, Diabetologie und Infektiologie | Hanau, Germany | Recruiting |
| KRH Klinikum Siloah, Klinik für Gastroenterologie | Hanover, Germany | Recruiting |
| Klinikum St. Georg gGmbH; Klinik für Gastroenterologie, Hepatologie, Diabetologie und Endokrinologie | Leipzig, Germany | Recruiting |
| University Hospital of Leipzig, Department of Gastroenterology | Leipzig, Germany | Recruiting |
+ 8 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05551299