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Study identifier: NCT05549297 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Condition: Advanced Melanoma  ·  Sponsor: Immunocore Ltd

PhasePhase 3
Planned participants540
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including clinical trials of investigational agents, salvage therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

Immunocore Medical Information  ·  844-466-8661  ·  medical.information@immunocore.com

Immunocore Medical Information EU  ·  +00 800-744-51111  ·  medinfo.eu@immunocore.com

Always discuss trial participation with your own doctor first.

Locations (82)

Mayo Clinic ArizonaPhoenix, Arizona, United StatesRecruiting
Mayo Clinic FloridaJacksonville, Florida, United StatesRecruiting
Orlando Health Cancer InstituteOrlando, Florida, United StatesRecruiting
Winship Cancer Institute of Emory UniversityAtlanta, Georgia, United StatesRecruiting
University of Kansas Cancer Center - WestwoodWestwood, Kansas, United StatesRecruiting
St Elizabeth Healthcare (St Elizabeth Medical Center)Edgewood, Kentucky, United StatesRecruiting
St Elizabeth Healthcare (St Elizabeth MedicalEdgewood, Kentucky, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Beth Israel Deaconess Medical Center (BIDMC)Boston, Massachusetts, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
University of Minnesota Medical CenterMinneapolis, Minnesota, United StatesRecruiting
Mayo Clinic MinnesotaRochester, Minnesota, United StatesRecruiting

+ 70 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05549297