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Study identifier: NCT05549102 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CBT and the Neural Circuits of Anxiety

Condition: Generalised Anxiety Disorder · Anxiety Disorders · CBT  ·  Sponsor: UCLH/UCL Joint Research Office

PhaseN/A
Planned participants174
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

This study will aim to test whether specific neural circuitry changes, proposed on the basis of a neurocognitive model of anxiety, are a mechanism of action for Cognitive Behavioural Therapy (CBT) interventions. This study aims to provide a theoretical model of the neurobiological mechanisms of CBT's therapeutic effect, where there currently is none, and potentially allow for more targeted/specific approaches to anxiety disorders following the identification of key CBT mechanisms. The ultimate aim is to improve the efficacy of CBT, and more generally, psychological interventions for anxiety disorders.

This description comes directly from the study's public registry record.

Talk to the study team

Emily Lewis  ·  02039872331  ·  emily.lewis.23@ucl.ac.uk

Oliver Robinson  ·  02076791150  ·  o.robinson@ucl.ac.uk

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Cognitive Neuroscience, University College LondonLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT05549102