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Study identifier: NCT05542056 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia

Condition: Thiazide-induced Hyponatremia (TIH)  ·  Sponsor: University Hospital, Basel, Switzerland

PhaseN/A
Planned participants232
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Thiazides and thiazide-like diuretics are one of the five major classes of antihypertensive drugs. This study is to investigate whether urinary PGE2 concentration at baseline (prior to thiazide initiation) is associated with the development of TIH within the first four weeks of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Julia Beck, Dr. med.  ·  +41 61 328 54 37  ·  julia.beck@usb.ch

Joyce Santos de Jesus  ·  joyce.santosdejesus@usb.ch

Always discuss trial participation with your own doctor first.

Locations (3)

Hospital Universitario de MóstolesMóstoles, SpainRecruiting
University Hospital Basel, Endocrinology, Diabetes and MetabolismBasel, SwitzerlandRecruiting
Kantonsspital BasellandLiestal, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05542056