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Study identifier: NCT05540834 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure

Condition: Acute Respiratory Failure · Hypercoagulability · Fibrinolysis Shutdown  ·  Sponsor: South West Sydney Local Health District

PhasePhase 2
Planned participants70
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Patients with coronavirus disease (COVID) and non-COVID acute respiratory failure (ARF) may be at an increased risk of thrombosis due to increased clot formation and decreased clot lysis. This two stage study aims to utilise bedside coagulation technology to detect patients at increased risk and guide tPA treatment to maximise efficacy and safety through a personalised approach.

This description comes directly from the study's public registry record.

Talk to the study team

Anders Aneman  ·  +61 427915693  ·  Anders.Aneman@health.nsw.gov.au

Lucy Coupland  ·  +61 419723330  ·  l.coupland@unsw.edu.au

Always discuss trial participation with your own doctor first.

Locations (1)

Intensive Care Unit, Liverpool Hospital, South Western Sydney Local Health DistrictLiverpool, New South Wales, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT05540834