Condition: COVID-19 · Sponsor: Ditte Gertz Mogensen
Aim: The aim is to investigate the effect of olfactory training with essential oils versus olfactory training with placebo-oils in patients with COVID-19 induced olfactory dysfunction Study design: The study is a placebo-controlled randomized clinical trial with an intervention group and a control group. The intervention group receive four essential oils with scents of orange, lavender, clove, and peppermint. Patients in the control group receive a fragrance kit, consisting of the same containers, but with fragrance-free oils added. Both groups are instructed to smell each of the four oils for 30 seconds in the morning and evening, over a three-month intervention period. Patients are given a diary in which to record their olfactory training. The nurse or medical student instructing the patients in the training and performing the smell and taste tests is blinded. Study population: Patients referred to the Unit for Sense of Taste and Smell in the Department of Otorhinolaryngology Head \& Neck and Audiology at Rigshospitalet. Inclusion criteria: * Impaired sense of taste and smell following COVID-19 \> 3 months * Hyposmia (16.25-30.5) or anosmia (\<16) assessed by Sniffin' Sticks Olfactory Test for Threshold, Discrimination and Identification (TDI) performed in the Unit for Sense of Taste and Smell with or without parosmia based on medical history * \> 18 years of age Exclusion criteria: * Cause of hyposmia, anosmia or parosmia other than COVID-19 * Does not read or speak …
This description comes directly from the study's public registry record.
Ditte G Gertz Mogensen, PhD-student · +45 35457508 · ditte.gertz.mogensen@regionh.dk
Vibeke Backer, Professor · +45 35456033 · nina.vibeke.backer@regionh.dk
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| Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University Hospital | Copenhagen, Denmark | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05539560