Condition: ICU Acquired Weakness · Post Intensive Care Unit Syndrome · Muscle Weakness · Sponsor: Esther Dupont-Versteegden
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which characteristics are associated with sustained physical disability. This proposal will examine muscle pathophysiology carefully aligned with physical function outcomes in order to longitudinally assess the recovery, or failed recovery, of muscle function in participants after critical illness: 1. to examine the recovery of muscle and physical function in ICU survivors through longitudinal assessments 2. to investigate the underlying cellular markers and mechanisms of muscle recovery in ICU survivors 3. to determine which cellular markers contribute to physical disability in ICU survivors up to 1 year after hospital admission
This description comes directly from the study's public registry record.
Kirby P Mayer, PhD · 859-218-0596 · kpmaye2@uky.edu
Doug Long, MS · 859-32-5438 · delong2@uky.edu
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham | Birmingham, Alabama, United States | Active Not Recruiting |
| University of Kentucky | Lexington, Kentucky, United States | Recruiting |
| Oklahoma Medical Research Foundation | Oklahoma City, Oklahoma, United States | Active Not Recruiting |
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Source record: clinicaltrials.gov/study/NCT05537298