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Study identifier: NCT05536076 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury

Condition: Sleep Apnea · SCI/D · Hypercapnia  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 89 Years
Healthy volunteersNo

About this study

It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A. the largest integrated health care system in the world for spinal cord injuries injury care. New therapies are needed to prevent the morbidities and mortalities associated with the high prevalence of respiratory disorders in Veterans with spinal cord injury. The current research project and future studies would set the base for developing innovative therapies for this disorder. This proposal addresses a new therapeutic intervention for sleep apnea in spinal cord injury. The investigators hypothesized that daily hypercapnia treatments improve respiratory symptoms and alleviate sleep apnea in patients with chronic spinal cord injury. The investigators will perform a pilot study to examine the impact of daily hypercapnia treatments for-two week durations among Veterans with spinal cord injury. The investigators believe that this novel approach to treating sleep apnea and will yield significant new knowledge that improves the health and quality of life of these patients.

This description comes directly from the study's public registry record.

Talk to the study team

Abdulghani Sankari, MD PhD  ·  (313) 576-1000  ·  Abdulghani.Sankari@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

John D. Dingell VA Medical Center, Detroit, MIDetroit, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05536076