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Study identifier: NCT05534087 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12)

Condition: Colon Cancer  ·  Sponsor: Seoul National University Hospital

PhasePhase 3
Planned participants236
Who can joinAll sexes, 19 Years to 75 Years
Healthy volunteersNo

About this study

This study is a prospective, open-label, randomized phase 3 clinical trial. It aims to investigate if the early introduction of intensified chemotherapy (3 months of modified FOLFIRINOX) improves the 3-year disease-free survival rate compared to standard treatment (FOLFOX/CAPOX for an additional three months to complete six months of standard adjuvant chemotherapy) in patients with stage 2-3 colon cancer in whom ctDNA MRD in the part 1 study remained positive during adjuvant FOLFOX/CAPOX chemotherapy

This description comes directly from the study's public registry record.

Talk to the study team

Sae-Won Han, MD,PhD  ·  82-2-2072-0795  ·  saewon1@snu.ac.kr

Youngjun Cha, MD  ·  82-2-2072-0795  ·  yongjuncha@ncc.re.kr

Always discuss trial participation with your own doctor first.

Locations (3)

National Cancer CenterGoyang, South KoreaRecruiting
Jin Won KimSeongnam, South KoreaRecruiting
Seoul National University HospitalSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT05534087