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Study identifier: NCT05533775 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Condition: Mature B-Cell Non-Hodgkin Lymphoma  ·  Sponsor: Hoffmann-La Roche

PhasePhase 1/Phase 2
Planned participants65
Who can joinAll sexes, 6 Months to 30 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of glofitamab, as monotherapy and in combination with a standard chemoimmunotherapy regimen: rituximab, ifosfamide, carboplatin, and etoposide (R-ICE) in pediatric and young adult participants with relapsed and refractory (R/R) mature B-cell non-Hodgkin lymphoma (B-NHL).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: CO43810 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (30)

Children's Hospital of AlabamaBirmingham, Alabama, United StatesRecruiting
UCSF Benioff Children's Hospital OaklandOakland, California, United StatesRecruiting
Kaiser Permanente Oakland Medical CenterOakland, California, United StatesRecruiting
Kaiser Permanente - RosevilleRoseville, California, United StatesRecruiting
Kaiser Permanente - Santa ClaraSanta Clara, California, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Childrens Mercy Hosp & ClinicsKansas City, Missouri, United StatesRecruiting
MSKCCNew York, New York, United StatesRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting
Queensland Children?s HospitalSouth Brisbane, Queensland, AustraliaRecruiting
Perth Children's HospitalNedlands, Western Australia, AustraliaRecruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05533775