● Recruiting

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Condition: Advanced Solid Tumors · Sponsor: ModernaTX, Inc.

PhasePhase 1/Phase 2

Planned participants361

Who can joinAll sexes, 12 Years to no upper limit

Healthy volunteersNo

About this study

The primary goal of this study is to assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab or ipilimumab and nivolumab.

This description comes directly from the study's public registry record.

Talk to the study team

Moderna WeCare Team · 1-866-663-3762 · WeCareClinicalTrials@modernatx.com

Always discuss trial participation with your own doctor first.

Locations (39)

The Angeles Clinic and Research Institute	Los Angeles, California, United States	Recruiting
UCSF Helen Diller Family Comprehensive Cancer Center	San Francisco, California, United States	Recruiting
University of Colorado Cancer Center	Aurora, Colorado, United States	Recruiting
George Washington University	Washington D.C., District of Columbia, United States	Recruiting
Orlando Health UF Health Cancer Center	Orlando, Florida, United States	Recruiting
The University of Chicago Medicine	Chicago, Illinois, United States	Recruiting
Massachusetts General Hospital	Boston, Massachusetts, United States	Recruiting
Dana Farber Cancer Institute	Boston, Massachusetts, United States	Recruiting
Henry Ford Hospital	Detroit, Michigan, United States	Recruiting
Washington University	St Louis, Missouri, United States	Recruiting
John Theurer Cancer Center	Hackensack, New Jersey, United States	Recruiting
NYU Langone Health-Perlmutter Cancer Center	New York, New York, United States	Recruiting

+ 27 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05533697